Ningkun王
Ningkun王 with a model of the X-ray crystallography structure of the human SIRT1 酶.
Exploring the effects of 酶 movement in cells
“自从我获得博士学位以来.D. advisor introduced me to the concept that proteins are not rigid — that they move, breathe and fluctuate — I’ve been fascinated by their ever-changing properties, and the importance of those properties in regulating protein function,” says Assistant Professor of Chemistry Ningkun王.
Her interest led to the work she and her students presently do at 菠菜网lol正规平台: conducting research into 酶s, a subset of proteins, specifically SIRT1. 调控的SIRT1 in the cell can alleviate the effects of age-related diseases such as Alzheimer’s 和糖尿病.
“Our research is in the early stages. But the data that we are collecting is giving us tantalizing hints on how different domains of SIRT1 move in response to a drug-like molecule. If we can understand how to artificially activate SIRT1 using drugs, then we have a new way to treat these diseases,” she explains.
Wang’s undergraduate and graduate students apply what they are learning in her classroom to their lab activities, and she praises their work.
“Students not only perform tasks in the lab, they also contribute intellectually to experimental design and conduct background literature research that help us gain new ideas and approach questions from different angles.”
Lab experience is also helping her students make decisions regarding what career path 遵循. Several have g一个 on to work in the biotech industry at companies such as Intuity Medical and Arcus Biosciences. Others are continuing their studies in order to pursue science-related careers, and 一个 of her students has been accepted to pharmacy school at the University of Colorado Anschutz Medical Campus.
菠菜网lol正规平台 student 安吉丽娜黄齐 looks for colony growth of BL21 (DE3) competent cells, E的变种. coli, on an agar plate containing Luria broth and Ampicillin antibiotic.
“During the master’s program, I gained a deeper understanding of complex research and technical concepts, preparing me for work in the biotech industry.”
安吉丽娜黄齐
20化学硕士
菠菜网lol正规平台 研究基金会 2020 年度报告
